RxHub is creating a universal, standardized communication framework that links prescribers, pharmacies, PBMs and benefits plans for the purpose of sharing prescription benefit information and exchanging prescriptions electronically - resulting in new efficiencies that keep health care safe and affordable. The three leading pharmacy benefit managers (PBMs) each independently recognized the value of electronic prescribing and it's most critical barrier - the lack of a common foundation. AdvancePCS, Express Scripts, and Medco Health Solutions were each pursuing electronic prescribing initiatives, but determined that a joint venture would be the optimal and most efficient way to accelerate the development of an industry-wide solution. In response to this challenge, RxHub was founded in 2001. By developing an open, health information exchange among all the parties in the prescribing industry, RxHub continues to demonstrate its ability to provide the interoperability needed to transform health care delivery through information technology.